DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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CGC
Degron:
NSVYSPGP
Uniprot ID:
P0CG00
Source protein:
Putative zinc finger and SCAN domain-containing protein 5D
Source gene:
ZSCAN5DP
Class:
CBL_PTK
Location:
327:334
E3 ligase:
CBL
DEGRON score:
0.9904
ASA_SCORE:
60.375
COIL:
0.7781
CONS_SCORE:
0.5063
DSS_SCORE:
0.5876
HELIX:
0.0298
FCONS_SCORE:
1.2394
RIG_SCORE:
0.6197
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZSCAN5DP mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of NSVYSPGP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P0CG00
Putative zinc finger and SCAN domain-containing protein 5D
CBL_PTK
327:334
NSVYSPGP
CBL
0.9904
More...
