DegronMD

Uniprot ID: Q10586

Source protein: D site-binding protein

Source gene: DBP

Class: DEG_SCF_FBW7_1

Location: 144:151

E3 ligase: FBXW7

DEGRON score: 0.9712

ASA_SCORE: 96.65

COIL: 0.9641

CONS_SCORE: 0.3736

DSS_SCORE: 0.7922

HELIX: 0.0131

FCONS_SCORE: 0.8894

RIG_SCORE: 0.4656

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P150S	DO229272	THCA	ICGC	PARTPAPS	DEG_SCF_FBW7_1	0.5641
p.G155D	ACH-000750	Skin Cancer	CCLE	PARTPAPS	DEG_SCF_FBW7_1	0.2222
p.A149V	ACH-001559	Lung Cancer	CCLE	PARTPAPS	DEG_SCF_FBW7_1	0.5825

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q10586	D site-binding protein	DEG_SCF_FBW7_1	144:151	PARTPAPS	FBXW7	0.9712	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons