DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PASTPSSE
Uniprot ID:
Q9UF83
Source protein:
Uncharacterized protein DKFZp434B061
Source gene:
-
Class:
DEG_SCF_FBW7_2
Location:
554:561
E3 ligase:
FBXW7
DEGRON score:
0.9331
ASA_SCORE:
95.7
COIL:
0.9699
CONS_SCORE:
0.4088
DSS_SCORE:
0.7435
HELIX:
0.0174
FCONS_SCORE:
1.1268
RIG_SCORE:
0.6489
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PASTPSSE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_SCF_FBW7_2
554:561
PASTPSSE
FBXW7
0.9331
More...