DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PATPRDE
Uniprot ID:
A6NFI3
Source protein:
Zinc finger protein 316
Source gene:
ZNF316
Class:
DEG_SCF_FBW7_2
Location:
126:132
E3 ligase:
FBXW7
DEGRON score:
0.9954
ASA_SCORE:
104.6429
COIL:
0.9151
CONS_SCORE:
0.4991
DSS_SCORE:
0.8723
HELIX:
0.0699
FCONS_SCORE:
1.1653
RIG_SCORE:
0.6106
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZNF316 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PATPRDE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NFI3
Zinc finger protein 316
DEG_SCF_FBW7_2
126:132
PATPRDE
FBXW7
0.9954
More...