DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
PCTPHPS
Uniprot ID:
Q8N377
Source protein:
Putative uncharacterized protein LOC387726
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
148:154
E3 ligase:
FBXW7
DEGRON score:
0.9199
ASA_SCORE:
78.3857
COIL:
0.7861
CONS_SCORE:
0
DSS_SCORE:
0.5975
HELIX:
0.137
FCONS_SCORE:
0
RIG_SCORE:
0.6693
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PCTPHPS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N377
Putative uncharacterized protein LOC387726
DEG_SCF_FBW7_1
148:154
PCTPHPS
FBXW7
0.9199
More...