DegronMD

Uniprot ID: O94832

Source protein: Unconventional myosin-Id

Source gene: MYO1D

Class: DEG_SCF_FBW7_1

Location: 832:838

E3 ligase: FBXW7

DEGRON score: 0.6036

ASA_SCORE: 87.3571

COIL: 0.8386

CONS_SCORE: 0.4674

DSS_SCORE: 0.43

HELIX: 0.1307

FCONS_SCORE: 0.8887

RIG_SCORE: 0.6702

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.W823G	SIDM00214	Colorectal Carcinoma	GDSC	PDTPQTS	DEG_SCF_FBW7_1	0.0833
p.W823G	SNU-407	large_intestine	COSMIC	PDTPQTS	DEG_SCF_FBW7_1	0.0833
p.N846S	ACH-000930	Breast Cancer	CCLE	PDTPQTS	DEG_SCF_FBW7_1	0.1111
p.D838G	ACH-002117	Bone Cancer	CCLE	PDTPQTS	DEG_SCF_FBW7_1	0.7198
p.D838G	EW-24	bone	COSMIC	PDTPQTS	DEG_SCF_FBW7_1	0.7198

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O94832	Unconventional myosin-Id	DEG_SCF_FBW7_1	832:838	PDTPQTS	FBXW7	0.6036	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons