DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PDYTPELE
Uniprot ID:
P12525
Source protein:
Putative myc-like protein MYCLP1
Source gene:
MYCLP1
Class:
DEG_SCF_FBW7_2
Location:
124:131
E3 ligase:
FBXW7
DEGRON score:
0.9975
ASA_SCORE:
75.1625
COIL:
0.81
CONS_SCORE:
0.3159
DSS_SCORE:
0.4523
HELIX:
0.1211
FCONS_SCORE:
1.5484
RIG_SCORE:
0.7729
Degron related mutations and impact score
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Drug responses associated with MYCLP1 mutations
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All proteins holding degron of PDYTPELE
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P12525
Putative myc-like protein MYCLP1
DEG_SCF_FBW7_2
124:131
PDYTPELE
FBXW7
0.9975
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