DegronMD

Uniprot ID: Q96EP9

Source protein: Sodium/bile acid cotransporter 4

Source gene: SLC10A4

Class: DEG_SCF_FBW7_2

Location: 60:67

E3 ligase: FBXW7

DEGRON score: 0.8476

ASA_SCORE: 81.4375

COIL: 0.9533

CONS_SCORE: 0.3675

DSS_SCORE: 0.7457

HELIX: 0.0148

FCONS_SCORE: 0.9511

RIG_SCORE: 0.5246

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G51R	DO233239	GACA	ICGC	PGPTPTPE	DEG_SCF_FBW7_2	0.0833
p.A74T	DO49201	PACA	ICGC	PGPTPTPE	DEG_SCF_FBW7_2	0.1389
p.G75C	ACH-001419	Breast Cancer	CCLE	PGPTPTPE	DEG_SCF_FBW7_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96EP9	Sodium/bile acid cotransporter 4	DEG_SCF_FBW7_2	60:67	PGPTPTPE	FBXW7	0.8476	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons