DegronMD

Uniprot ID: Q14696

Source protein: LRP chaperone MESD

Source gene: MESD

Class: DEG_SCF_FBW7_1

Location: 38:44

E3 ligase: FBXW7

DEGRON score: 0.5187

ASA_SCORE: 85.1

COIL: 0.9274

CONS_SCORE: 0.2965

DSS_SCORE: 0.7488

HELIX: 0.0404

FCONS_SCORE: 0.7864

RIG_SCORE: 0.5211

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E43G	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	PGTPDES	DEG_SCF_FBW7_1	0.6087
p.E43G	T-T	oesophagus	COSMIC	PGTPDES	DEG_SCF_FBW7_1	0.6087

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q14696	LRP chaperone MESD	DEG_SCF_FBW7_1	38:44	PGTPDES	FBXW7	0.5187	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons