DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PGTPESS
Uniprot ID:
Q9P1D8
Source protein:
Putative uncharacterized protein PRO2289
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
27:33
E3 ligase:
FBXW7
DEGRON score:
0.689
ASA_SCORE:
74.8571
COIL:
0.8507
CONS_SCORE:
0
DSS_SCORE:
0.7657
HELIX:
0.0889
FCONS_SCORE:
0
RIG_SCORE:
0.5536
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PGTPESS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9P1D8
Putative uncharacterized protein PRO2289
DEG_SCF_FBW7_1
27:33
PGTPESS
FBXW7
0.689
More...