DegronMD

Uniprot ID: O75956

Source protein: Cyclin-dependent kinase 2-associated protein 2

Source gene: CDK2AP2

Class: DEG_SCF_FBW7_1

Location: 21:27

E3 ligase: FBXW7

DEGRON score: 0.7672

ASA_SCORE: 90.4286

COIL: 0.9624

CONS_SCORE: 0.437

DSS_SCORE: 0.6962

HELIX: 0.0099

FCONS_SCORE: 0.8851

RIG_SCORE: 0.5035

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P33L	DO218065	BRCA	ICGC	PGTPVPT	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O75956	Cyclin-dependent kinase 2-associated protein 2	DEG_SCF_FBW7_1	21:27	PGTPVPT	FBXW7	0.7672	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons