DegronMD

Uniprot ID: Q9HD33

Source protein: 39S ribosomal protein L47, mitochondrial

Source gene: MRPL47

Class: DEG_SCF_FBW7_1

Location: 40:47

E3 ligase: FBXW7

DEGRON score: 0.5691

ASA_SCORE: 82.025

COIL: 0.8999

CONS_SCORE: 0.2321

DSS_SCORE: 0.1266

HELIX: 0.0415

FCONS_SCORE: 0.9914

RIG_SCORE: 0.7336

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q51K	DO228978	LICA	ICGC	PKSTPNVT	DEG_SCF_FBW7_1	0.2222
p.P44Q	DO229018	LICA	ICGC	PKSTPNVT	DEG_SCF_FBW7_1	0.7035
p.N53H	NOMO-1	haematopoietic_and_lymphoid_tissue	COSMIC	PKSTPNVT	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9HD33	39S ribosomal protein L47, mitochondrial	DEG_SCF_FBW7_1	40:47	PKSTPNVT	FBXW7	0.5691	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons