DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PKTTPSPS
Uniprot ID:
Q75MW2
Source protein:
Protein ZNF767
Source gene:
ZNF767P
Class:
DEG_SCF_FBW7_1
Location:
107:114
E3 ligase:
FBXW7
DEGRON score:
0.8182
ASA_SCORE:
77.9125
COIL:
0.917
CONS_SCORE:
0
DSS_SCORE:
0.8315
HELIX:
0.019
FCONS_SCORE:
0
RIG_SCORE:
0.5204
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZNF767P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PKTTPSPS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q75MW2
Protein ZNF767
DEG_SCF_FBW7_1
107:114
PKTTPSPS
FBXW7
0.8182
More...