DegronMD

Uniprot ID: Q9BW85

Source protein: Splicing factor YJU2

Source gene: YJU2

Class: DEG_SCF_FBW7_1

Location: 299:305

E3 ligase: FBXW7

DEGRON score: 0.9779

ASA_SCORE: 76.7143

COIL: 0.8913

CONS_SCORE: 0.2784

DSS_SCORE: 0.7201

HELIX: 0.0424

FCONS_SCORE: 0.8857

RIG_SCORE: 0.6206

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D315Y	SIDM00718	Non-Small Cell Lung Carcinoma	GDSC	PLTPGAS	DEG_SCF_FBW7_1	0.0556
p.D315Y	NCI-H358	lung	COSMIC	PLTPGAS	DEG_SCF_FBW7_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BW85	Splicing factor YJU2	DEG_SCF_FBW7_1	299:305	PLTPGAS	FBXW7	0.9779	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons