DegronMD

Uniprot ID: P23246

Source protein: Splicing factor, proline- and glutamine-rich

Source gene: SFPQ

Class: DEG_SCF_FBW7_1

Location: 132:139

E3 ligase: FBXW7

DEGRON score: 0.8311

ASA_SCORE: 99.65

COIL: 0.9806

CONS_SCORE: 0.3217

DSS_SCORE: 0.755

HELIX: 0.0087

FCONS_SCORE: 0.9858

RIG_SCORE: 0.4539

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P125L	ACH-000985	Colon/Colorectal Cancer	CCLE	PPATPPTS	DEG_SCF_FBW7_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P23246	Splicing factor, proline- and glutamine-rich	DEG_SCF_FBW7_1	132:139	PPATPPTS	FBXW7	0.8311	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons