DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
PPLTPGLS
Uniprot ID:
A6NIE9
Source protein:
Putative serine protease 29
Source gene:
PRSS29P
Class:
DEG_SCF_FBW7_1
Location:
19:26
E3 ligase:
FBXW7
DEGRON score:
0.932
ASA_SCORE:
76.2375
COIL:
0.9634
CONS_SCORE:
0.0979
DSS_SCORE:
0.7208
HELIX:
0.0175
FCONS_SCORE:
0.5465
RIG_SCORE:
0.5691
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with PRSS29P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PPLTPGLS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NIE9
Putative serine protease 29
DEG_SCF_FBW7_1
19:26
PPLTPGLS
FBXW7
0.932
More...