DegronMD

Uniprot ID: Q66K41

Source protein: Zinc finger protein 385C

Source gene: ZNF385C

Class: DEG_SCF_FBW7_1

Location: 157:164

E3 ligase: FBXW7

DEGRON score: 0.9885

ASA_SCORE: 82.1875

COIL: 0.922

CONS_SCORE: 0.4419

DSS_SCORE: 0.7806

HELIX: 0.0397

FCONS_SCORE: 1.1609

RIG_SCORE: 0.55

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.F157L	DO229018	LICA	ICGC	PPPTPDPT	DEG_SCF_FBW7_1	0.6981
p.K155Q	ACH-000120	Neuroblastoma	CCLE	PPPTPDPT	DEG_SCF_FBW7_1	0.2778
p.K155Q	CHP-212	autonomic_ganglia	COSMIC	PPPTPDPT	DEG_SCF_FBW7_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q66K41	Zinc finger protein 385C	DEG_SCF_FBW7_1	157:164	PPPTPDPT	FBXW7	0.9885	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons