DegronMD

Uniprot ID: Q5W0A0

Source protein: Glutamate-rich protein 6B

Source gene: ERICH6B

Class: DEG_SCF_FBW7_1

Location: 16:23

E3 ligase: FBXW7

DEGRON score: 0.9426

ASA_SCORE: 96.6875

COIL: 0.9365

CONS_SCORE: 0.302

DSS_SCORE: 0.8772

HELIX: 0.0373

FCONS_SCORE: 1.0776

RIG_SCORE: 0.5518

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L8F	SIDM00935	Other Solid Cancers	GDSC	PPTTPQYS	DEG_SCF_FBW7_1	0.1111
p.L8F	CAL-39	vulva	COSMIC	PPTTPQYS	DEG_SCF_FBW7_1	0.1111
p.Q21K	TC-71	bone	COSMIC	PPTTPQYS	DEG_SCF_FBW7_1	0.5833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5W0A0	Glutamate-rich protein 6B	DEG_SCF_FBW7_1	16:23	PPTTPQYS	FBXW7	0.9426	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons