DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
PQTPSAS
Uniprot ID:
Q8NBZ9
Source protein:
Putative uncharacterized protein NEXN-AS1
Source gene:
NEXN-AS1
Class:
DEG_SCF_FBW7_1
Location:
149:155
E3 ligase:
FBXW7
DEGRON score:
0.7835
ASA_SCORE:
80.3857
COIL:
0.8541
CONS_SCORE:
0
DSS_SCORE:
0.8818
HELIX:
0.1327
FCONS_SCORE:
0
RIG_SCORE:
0.5113
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with NEXN-AS1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PQTPSAS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NBZ9
Putative uncharacterized protein NEXN-AS1
DEG_SCF_FBW7_1
149:155
PQTPSAS
FBXW7
0.7835
More...