DegronMD

Uniprot ID: P83369

Source protein: U7 snRNA-associated Sm-like protein LSm11

Source gene: LSM11

Class: DEG_APCC_DBOX_1

Location: 141:149

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.987

ASA_SCORE: 81.9889

COIL: 0.6813

CONS_SCORE: 0.5863

DSS_SCORE: 0.6236

HELIX: 0.1813

FCONS_SCORE: 1.0923

RIG_SCORE: 0.702

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G157C	TCGA-AX-A060	UCEC	TCGA	PRNVLTRMP	DEG_APCC_DBOX_1	0.1111
p.G157C	DO42576	UCEC	ICGC	PRNVLTRMP	DEG_APCC_DBOX_1	0.1111
p.P155T	DO228757	PRAD	ICGC	PRNVLTRMP	DEG_APCC_DBOX_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P83369	U7 snRNA-associated Sm-like protein LSm11	DEG_APCC_DBOX_1	141:149	PRNVLTRMP	APC,CDC20,FZR1	0.987	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons