DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
PRTPPMT
Uniprot ID:
I3L1E1
Source protein:
Uncharacterized protein C19orf84
Source gene:
C19orf84
Class:
DEG_SCF_FBW7_1
Location:
144:150
E3 ligase:
FBXW7
DEGRON score:
0.9801
ASA_SCORE:
97.7714
COIL:
0.9464
CONS_SCORE:
0.7142
DSS_SCORE:
0.8864
HELIX:
0.012
FCONS_SCORE:
1.3095
RIG_SCORE:
0.5335
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with C19orf84 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PRTPPMT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
I3L1E1
Uncharacterized protein C19orf84
DEG_SCF_FBW7_1
144:150
PRTPPMT
FBXW7
0.9801
More...