DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
PSTPPQS
Uniprot ID:
Q1RN00
Source protein:
Putative uncharacterized protein LOC151760
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
44:50
E3 ligase:
FBXW7
DEGRON score:
0.9786
ASA_SCORE:
74.4143
COIL:
0.9543
CONS_SCORE:
0.7869
DSS_SCORE:
0.8311
HELIX:
0.0254
FCONS_SCORE:
1.1661
RIG_SCORE:
0.5051
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PSTPPQS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q1RN00
Putative uncharacterized protein LOC151760
DEG_SCF_FBW7_1
44:50
PSTPPQS
FBXW7
0.9786
More...