DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
PTPATT
Uniprot ID:
P0C841
Source protein:
Putative protein FAM66E
Source gene:
FAM66E
Class:
DEG_SCF_FBW7_1
Location:
27:32
E3 ligase:
FBXW7
DEGRON score:
0.9887
ASA_SCORE:
66.85
COIL:
0.8723
CONS_SCORE:
0
DSS_SCORE:
0.6154
HELIX:
0.014
FCONS_SCORE:
0
RIG_SCORE:
0.6821
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with FAM66E mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTPATT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P0C841
Putative protein FAM66E
DEG_SCF_FBW7_1
27:32
PTPATT
FBXW7
0.9887
More...