DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTPLRT
Uniprot ID:
P59797
Source protein:
Selenoprotein V
Source gene:
SELENOV
Class:
DEG_SCF_FBW7_1
Location:
28:33
E3 ligase:
FBXW7
DEGRON score:
0.9952
ASA_SCORE:
101.5833
COIL:
0.9607
CONS_SCORE:
0.6777
DSS_SCORE:
0.8074
HELIX:
0.0112
FCONS_SCORE:
1.2057
RIG_SCORE:
0.6439
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SELENOV mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTPLRT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P59797
Selenoprotein V
DEG_SCF_FBW7_1
28:33
PTPLRT
FBXW7
0.9952
More...