DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTPPDS
Uniprot ID:
Q6ZRN7
Source protein:
Putative uncharacterized protein FLJ46214
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
22:27
E3 ligase:
FBXW7
DEGRON score:
0.9385
ASA_SCORE:
86.15
COIL:
0.9688
CONS_SCORE:
1
DSS_SCORE:
0.7576
HELIX:
0.0145
FCONS_SCORE:
1
RIG_SCORE:
0.5536
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTPPDS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZRN7
Putative uncharacterized protein FLJ46214
DEG_SCF_FBW7_1
22:27
PTPPDS
FBXW7
0.9385
More...