DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTPVRT
Uniprot ID:
P59797
Source protein:
Selenoprotein V
Source gene:
SELENOV
Class:
DEG_SCF_FBW7_1
Location:
34:39
E3 ligase:
FBXW7
DEGRON score:
0.7745
ASA_SCORE:
99.6
COIL:
0.9472
CONS_SCORE:
0.5252
DSS_SCORE:
0.7565
HELIX:
0.012
FCONS_SCORE:
0.9388
RIG_SCORE:
0.7027
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SELENOV mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTPVRT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P59797
Selenoprotein V
DEG_SCF_FBW7_1
34:39
PTPVRT
FBXW7
0.7745
More...