DegronMD

Uniprot ID: Q9Y3T6

Source protein: R3H and coiled-coil domain-containing protein 1

Source gene: R3HCC1

Class: DEG_APCC_DBOX_1

Location: 395:403

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6935

ASA_SCORE: 86.0556

COIL: 0.5177

CONS_SCORE: 0.5337

DSS_SCORE: 0.4204

HELIX: 0.4583

FCONS_SCORE: 1.0499

RIG_SCORE: 0.8249

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G398S	ACH-000203	Neuroblastoma	CCLE	QRPKLLRLV	DEG_APCC_DBOX_1	0.6993

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9Y3T6	R3H and coiled-coil domain-containing protein 1	DEG_APCC_DBOX_1	395:403	QRPKLLRLV	APC,CDC20,FZR1	0.6935	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons