DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
QRRKLDPLL
Uniprot ID:
Q1RN00
Source protein:
Putative uncharacterized protein LOC151760
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
5:13
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9618
ASA_SCORE:
112.5333
COIL:
0.7513
CONS_SCORE:
0.8173
DSS_SCORE:
0.7155
HELIX:
0.2214
FCONS_SCORE:
1.2303
RIG_SCORE:
0.7594
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of QRRKLDPLL
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q1RN00
Putative uncharacterized protein LOC151760
DEG_APCC_DBOX_1
5:13
QRRKLDPLL
APC,CDC20,FZR1
0.9618
More...