DegronMD

Uniprot ID: P19784

Source protein: Casein kinase II subunit alpha'

Source gene: CSNK2A2

Class: LIG_APCC_ABBAyCdc20_2

Location: 9:15

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9887

ASA_SCORE: 82.6571

COIL: 0.429

CONS_SCORE: 0.626

DSS_SCORE: 0.3445

HELIX: 0.3163

FCONS_SCORE: 1.2894

RIG_SCORE: 0.7831

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V16A	TCGA-A6-3809	COAD	TCGA	RARVYAE	LIG_APCC_ABBAyCdc20_2	0.3056
p.V16A	DO8722	COAD	ICGC	RARVYAE	LIG_APCC_ABBAyCdc20_2	0.3056
p.A10V	DO232761	PBCA	ICGC	RARVYAE	LIG_APCC_ABBAyCdc20_2	0.5825

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P19784	Casein kinase II subunit alpha'	LIG_APCC_ABBAyCdc20_2	9:15	RARVYAE	APC,CDC20,FZR1	0.9887	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons