DegronMD

Uniprot ID: Q9H0X4

Source protein: Protein FAM234A

Source gene: FAM234A

Class: LIG_APCC_ABBAyCdc20_2

Location: 395:401

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5369

ASA_SCORE: 26.9714

COIL: 0.2449

CONS_SCORE: 0.4528

DSS_SCORE: 0.1521

HELIX: 0.0131

FCONS_SCORE: 0.8682

RIG_SCORE: 0.9425

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V385L	SIDM00344	Non-Small Cell Lung Carcinoma	GDSC	RQILFLD	LIG_APCC_ABBAyCdc20_2	0.0556
p.V385L	LCLC-97TM1	lung	COSMIC	RQILFLD	LIG_APCC_ABBAyCdc20_2	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H0X4	Protein FAM234A	LIG_APCC_ABBAyCdc20_2	395:401	RQILFLD	APC,CDC20,FZR1	0.5369	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons