DegronMD

Uniprot ID: Q86Y56

Source protein: Dynein axonemal assembly factor 5

Source gene: DNAAF5

Class: DEG_APCC_DBOX_1

Location: 46:54

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5894

ASA_SCORE: 48.3667

COIL: 0.0033

CONS_SCORE: 0.4888

DSS_SCORE: 0.4893

HELIX: 0.996

FCONS_SCORE: 1.2205

RIG_SCORE: 0.7339

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T56I	COLO-783	skin	COSMIC	RRRALEALR	DEG_APCC_DBOX_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q86Y56	Dynein axonemal assembly factor 5	DEG_APCC_DBOX_1	46:54	RRRALEALR	APC,CDC20,FZR1	0.5894	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons