DegronMD

Uniprot ID: Q8N5H3

Source protein: Leucine repeat adapter protein 25

Source gene: FAM89B

Class: LIG_APCC_ABBAyCdc20_2

Location: 48:54

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9272

ASA_SCORE: 102.6

COIL: 0.492

CONS_SCORE: 0.73

DSS_SCORE: 0.4674

HELIX: 0.489

FCONS_SCORE: 1.0084

RIG_SCORE: 0.7384

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D53E	ACH-001329	Brain Cancer	CCLE	RSRIHDE	LIG_APCC_ABBAyCdc20_2	0.5647

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N5H3	Leucine repeat adapter protein 25	LIG_APCC_ABBAyCdc20_2	48:54	RSRIHDE	APC,CDC20,FZR1	0.9272	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons