DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
SLEDGSVPEI
Uniprot ID:
Q58G82
Source protein:
Putative synaptotagmin-14-like protein
Source gene:
SYT14P1
Class:
DEG_COP1_1
Location:
44:53
E3 ligase:
COP1
DEGRON score:
0.7247
ASA_SCORE:
63.86
COIL:
0.7185
CONS_SCORE:
0.4273
DSS_SCORE:
0.1799
HELIX:
0.0258
FCONS_SCORE:
0.8129
RIG_SCORE:
0.7753
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SYT14P1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SLEDGSVPEI
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q58G82
Putative synaptotagmin-14-like protein
DEG_COP1_1
44:53
SLEDGSVPEI
COP1
0.7247
More...