DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
SLEPEVPTP
Uniprot ID:
A8MZF0
Source protein:
Proline-rich protein 33
Source gene:
PRR33
Class:
DEG_COP1_1
Location:
215:223
E3 ligase:
COP1
DEGRON score:
0.957
ASA_SCORE:
103.6889
COIL:
0.9579
CONS_SCORE:
0.5328
DSS_SCORE:
0.7873
HELIX:
0.0233
FCONS_SCORE:
0.8566
RIG_SCORE:
0.5812
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with PRR33 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SLEPEVPTP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MZF0
Proline-rich protein 33
DEG_COP1_1
215:223
SLEPEVPTP
COP1
0.957
More...