DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
SRASLMKME
Uniprot ID:
Q9UF83
Source protein:
Uncharacterized protein DKFZp434B061
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
296:304
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9732
ASA_SCORE:
107.3778
COIL:
0.9301
CONS_SCORE:
0.3827
DSS_SCORE:
0.6729
HELIX:
0.0491
FCONS_SCORE:
0.9687
RIG_SCORE:
0.6891
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SRASLMKME
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_APCC_DBOX_1
296:304
SRASLMKME
APC,CDC20,FZR1
0.9732
More...