DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
SREQLAALK
Uniprot ID:
Q9UII2
Source protein:
ATPase inhibitor, mitochondrial
Source gene:
ATP5IF1
Class:
DEG_APCC_DBOX_1
Location:
63:71
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6386
ASA_SCORE:
88.4444
COIL:
0.0492
CONS_SCORE:
0.7265
DSS_SCORE:
0.488
HELIX:
0.9506
FCONS_SCORE:
0.9889
RIG_SCORE:
0.7009
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ATP5IF1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SREQLAALK
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UII2
ATPase inhibitor, mitochondrial
DEG_APCC_DBOX_1
63:71
SREQLAALK
APC,CDC20,FZR1
0.6386
More...