DegronMD

Uniprot ID: Q99613

Source protein: Eukaryotic translation initiation factor 3 subunit C

Source gene: EIF3C

Class: DEG_APCC_DBOX_1

Location: 208:216

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9923

ASA_SCORE: 98.1889

COIL: 0.3893

CONS_SCORE: 0.3287

DSS_SCORE: 0.6465

HELIX: 0.5891

FCONS_SCORE: 1.0638

RIG_SCORE: 0.6932

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E226G	ACH-000936	Ovarian Cancer	CCLE	SRKFLKKMD	DEG_APCC_DBOX_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q99613	Eukaryotic translation initiation factor 3 subunit C	DEG_APCC_DBOX_1	208:216	SRKFLKKMD	APC,CDC20,FZR1	0.9923	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons