DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
SRPNLSFLL
Uniprot ID:
Q8NBF4
Source protein:
Putative uncharacterized protein FLJ33307
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
67:75
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6923
ASA_SCORE:
63.1333
COIL:
0.4754
CONS_SCORE:
0
DSS_SCORE:
0.3758
HELIX:
0.0144
FCONS_SCORE:
0
RIG_SCORE:
0.7489
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SRPNLSFLL
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NBF4
Putative uncharacterized protein FLJ33307
DEG_APCC_DBOX_1
67:75
SRPNLSFLL
APC,CDC20,FZR1
0.6923
More...