DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
SSRPPVPDY
Uniprot ID:
Q8ND07
Source protein:
Basal body-orientation factor 1
Source gene:
BBOF1
Class:
DEG_COP1_1
Location:
468:476
E3 ligase:
COP1
DEGRON score:
0.9234
ASA_SCORE:
94.9
COIL:
0.9636
CONS_SCORE:
0.723
DSS_SCORE:
0.5346
HELIX:
0.0166
FCONS_SCORE:
0.9867
RIG_SCORE:
0.6492
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with BBOF1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SSRPPVPDY
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8ND07
Basal body-orientation factor 1
DEG_COP1_1
468:476
SSRPPVPDY
COP1
0.9234
More...