DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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CGC
Degron:
SSSGKSSLVPSP
Uniprot ID:
Q8NAJ2
Source protein:
Putative uncharacterized protein encoded by LINC02913
Source gene:
LINC02913
Class:
DEG_COP1_1
Location:
56:67
E3 ligase:
COP1
DEGRON score:
0.9337
ASA_SCORE:
76.85
COIL:
0.9317
CONS_SCORE:
0
DSS_SCORE:
0.4456
HELIX:
0.0228
FCONS_SCORE:
0
RIG_SCORE:
0.5717
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with LINC02913 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SSSGKSSLVPSP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NAJ2
Putative uncharacterized protein encoded by LINC02913
DEG_COP1_1
56:67
SSSGKSSLVPSP
COP1
0.9337
More...