DegronMD

Uniprot ID: Q9UPZ9

Source protein: Serine/threonine-protein kinase ICK

Source gene: CILK1

Class: DEG_COP1_1

Location: 547:559

E3 ligase: COP1

DEGRON score: 0.8458

ASA_SCORE: 69.7462

COIL: 0.8022

CONS_SCORE: 0.3477

DSS_SCORE: 0.3513

HELIX: 0.1296

FCONS_SCORE: 1.1218

RIG_SCORE: 0.6952

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S548P	SIDM00068	Colorectal Carcinoma	GDSC	SSSGLTGNYVPSF	DEG_COP1_1	0.6752

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UPZ9	Serine/threonine-protein kinase ICK	DEG_COP1_1	547:559	SSSGLTGNYVPSF	COP1	0.8458	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons