DegronMD

Uniprot ID: Q93015

Source protein: N-alpha-acetyltransferase 80

Source gene: NAA80

Class: DEG_COP1_1

Location: 252:261

E3 ligase: COP1

DEGRON score: 0.996

ASA_SCORE: 80.86

COIL: 0.9698

CONS_SCORE: 0.4411

DSS_SCORE: 0.6099

HELIX: 0.0106

FCONS_SCORE: 0.9126

RIG_SCORE: 0.5811

Degron related mutations and impact score

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R244W	SIDM00578	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00216	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01034	B-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00373	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00961	Ewing's Sarcoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00074	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00588	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00450	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00570	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00425	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00586	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00993	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00557	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00582	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00435	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00338	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00958	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00321	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01037	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01020	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00215	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00371	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00615	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00773	Non-Cancerous	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00234	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00390	T-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00232	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00617	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00572	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00759	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00611	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00845	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01090	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00111	Glioma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01040	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01237	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00113	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01197	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00565	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00352	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00678	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00491	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00535	Chondrosarcoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01030	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00781	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00600	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00602	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01199	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00496	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00367	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00291	Melanoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00281	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00544	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01038	B-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00553	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00087	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00846	Cervical Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00633	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00607	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00463	T-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00315	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00308	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01005	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00193	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00057	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00465	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00296	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00581	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00573	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00589	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00002	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00552	Rhabdomyosarcoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00293	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00690	Head and Neck Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00592	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00457	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00356	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00533	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00355	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00040	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00350	Head and Neck Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00529	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01181	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00260	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01196	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00619	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01093	Cervical Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00687	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00287	B-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00556	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01247	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00235	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00562	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00358	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01172	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00383	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00585	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00587	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00487	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00143	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00251	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00054	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00489	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00292	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00290	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00564	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00498	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00488	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01146	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00365	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00410	Other Blood Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00526	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00276	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00214	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00298	Squamous Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00844	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00567	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00240	Cervical Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01653	Non-Cancerous	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00997	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00357	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01019	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00907	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00576	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00574	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01210	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00283	B-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00280	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00580	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00970	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00397	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00207	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00618	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00989	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00988	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00616	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00655	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00793	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01217	Other Blood Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01133	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00271	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00469	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00324	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00613	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01257	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00217	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00431	T-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00986	Head and Neck Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01010	T-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00380	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00361	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00289	B-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00996	Thyroid Gland Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00045	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00448	B-Cell Non-Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00850	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00233	T-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00316	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00554	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00349	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00503	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00083	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00302	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00604	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00774	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01018	Hodgkin's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00257	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00026	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00808	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00760	Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01033	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00273	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00575	Glioma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01173	Rhabdomyosarcoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00359	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00531	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01727	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01439	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01695	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00192	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01728	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01609	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01608	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01569	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01612	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00165	Other Solid Cancers	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01449	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01682	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01617	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01570	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00168	Head and Neck Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01498	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01470	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01412	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01460	Glioma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01393	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01660	Kidney Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01622	Breast Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01368	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01444	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01781	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01377	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01578	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00062	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00008	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01336	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00160	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01611	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01776	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00158	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01471	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01472	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01573	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01347	Ovarian Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00780	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01469	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00784	Glioma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00248	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00161	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01494	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00163	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01435	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01575	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01446	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01447	Glioblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01691	Chronic Myelogenous Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01450	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01690	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01658	Unknown	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01321	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00959	Acute Myeloid Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01559	Melanoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01413	Oral Cavity Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00171	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01662	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01587	Bladder Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01694	B-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00016	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01473	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01451	Pancreatic Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01574	Plasma Cell Myeloma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01763	Rhabdomyosarcoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01391	Neuroblastoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01442	Glioma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00162	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01434	Hepatocellular Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01343	Gastric Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00015	Esophageal Squamous Cell Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01254	Burkitt's Lymphoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01729	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00159	Biliary Tract Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01619	Endometrial Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM00497	Colorectal Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.R244W	SIDM01618	B-Lymphoblastic Leukemia	GDSC	TISPPVPSGP	DEG_COP1_1	0.1111
p.N248Y	SIDM00658	Non-Small Cell Lung Carcinoma	GDSC	TISPPVPSGP	DEG_COP1_1	0.2222
p.N248Y	NCI-H1435	lung	COSMIC	TISPPVPSGP	DEG_COP1_1	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: TISPPVPSGP

Degron related mutations and impact score

Drug responses associated with NAA80 mutations

All proteins holding degron of TISPPVPSGP

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q93015	N-alpha-acetyltransferase 80	DEG_COP1_1	252:261	TISPPVPSGP	COP1	0.996	More...