DegronMD

Uniprot ID: Q8IXW0

Source protein: Lamin tail domain-containing protein 2

Source gene: LMNTD2

Class: DEG_APCC_DBOX_1

Location: 526:534

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6103

ASA_SCORE: 87.5222

COIL: 0.932

CONS_SCORE: 0.3078

DSS_SCORE: 0.7061

HELIX: 0.0199

FCONS_SCORE: 0.8327

RIG_SCORE: 0.6047

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A541T	SIDM01004	Chronic Myelogenous Leukemia	GDSC	TRGLLPPVS	DEG_APCC_DBOX_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IXW0	Lamin tail domain-containing protein 2	DEG_APCC_DBOX_1	526:534	TRGLLPPVS	APC,CDC20,FZR1	0.6103	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons