DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
TRGQLHVLR
Uniprot ID:
B0FP48
Source protein:
Uroplakin-3b-like protein 1
Source gene:
UPK3BL1
Class:
DEG_APCC_DBOX_1
Location:
129:137
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.744
ASA_SCORE:
58.8556
COIL:
0.5041
CONS_SCORE:
0.6108
DSS_SCORE:
0.2858
HELIX:
0.0239
FCONS_SCORE:
0.853
RIG_SCORE:
0.8128
Degron related mutations and impact score
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Drug responses associated with UPK3BL1 mutations
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All proteins holding degron of TRGQLHVLR
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
B0FP48
Uroplakin-3b-like protein 1
DEG_APCC_DBOX_1
129:137
TRGQLHVLR
APC,CDC20,FZR1
0.744
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E5RIL1
Uroplakin-3b-like protein 2
DEG_APCC_DBOX_1
129:137
TRGQLHVLR
APC,CDC20,FZR1
0.744
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