DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
TRLPLGSLM
Uniprot ID:
Q5VWM4
Source protein:
PRAME family member 8
Source gene:
PRAMEF8
Class:
DEG_APCC_DBOX_1
Location:
62:70
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.918
ASA_SCORE:
48.7333
COIL:
0.7207
CONS_SCORE:
0.788
DSS_SCORE:
0.187
HELIX:
0.1783
FCONS_SCORE:
1.1527
RIG_SCORE:
0.7881
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with PRAMEF8 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of TRLPLGSLM
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5VWM4
PRAME family member 8
DEG_APCC_DBOX_1
62:70
TRLPLGSLM
APC,CDC20,FZR1
0.918
More...