DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
TRPESIFVPTA
Uniprot ID:
Q9BRP9
Source protein:
Putative uncharacterized protein MGC13053
Source gene:
-
Class:
DEG_COP1_1
Location:
96:106
E3 ligase:
COP1
DEGRON score:
0.8994
ASA_SCORE:
61.0818
COIL:
0.5986
CONS_SCORE:
0
DSS_SCORE:
0.6379
HELIX:
0.077
FCONS_SCORE:
0
RIG_SCORE:
0.7034
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of TRPESIFVPTA
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9BRP9
Putative uncharacterized protein MGC13053
DEG_COP1_1
96:106
TRPESIFVPTA
COP1
0.8994
More...