DegronMD

Uniprot ID: Q3SY00

Source protein: Testis-specific protein 10-interacting protein

Source gene: TSGA10IP

Class: DEG_APCC_DBOX_1

Location: 33:41

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5794

ASA_SCORE: 43.4667

COIL: 0.2166

CONS_SCORE: 0.6385

DSS_SCORE: 0.4535

HELIX: 0.7526

FCONS_SCORE: 1.4033

RIG_SCORE: 0.7823

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D25E	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	TRTGLLKLL	DEG_APCC_DBOX_1	0.1111
p.D25E	SIDM00845	Burkitt's Lymphoma	GDSC	TRTGLLKLL	DEG_APCC_DBOX_1	0.1111
p.D25E	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	TRTGLLKLL	DEG_APCC_DBOX_1	0.1111
p.D25E	SIDM00760	Small Cell Lung Carcinoma	GDSC	TRTGLLKLL	DEG_APCC_DBOX_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q3SY00	Testis-specific protein 10-interacting protein	DEG_APCC_DBOX_1	33:41	TRTGLLKLL	APC,CDC20,FZR1	0.5794	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons