DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
VETPQIS
Uniprot ID:
A6NJ88
Source protein:
Putative SAGE1-like protein
Source gene:
SAGE2P
Class:
DEG_SCF_FBW7_1
Location:
518:524
E3 ligase:
FBXW7
DEGRON score:
0.6485
ASA_SCORE:
82.5143
COIL:
0.891
CONS_SCORE:
0
DSS_SCORE:
0.468
HELIX:
0.0391
FCONS_SCORE:
0
RIG_SCORE:
0.7347
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SAGE2P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VETPQIS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NJ88
Putative SAGE1-like protein
DEG_SCF_FBW7_1
518:524
VETPQIS
FBXW7
0.6485
More...