DegronMD

Uniprot ID: Q16829

Source protein: Dual specificity protein phosphatase 7

Source gene: DUSP7

Class: LIG_APCC_ABBA_1

Location: 133:138

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7269

ASA_SCORE: 19.1167

COIL: 0.3007

CONS_SCORE: 0.4354

DSS_SCORE: 0.216

HELIX: 0.0117

FCONS_SCORE: 1.3755

RIG_SCORE: 0.867

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G123S	DO220881	MELA	ICGC	VLLYDE	LIG_APCC_ABBA_1	0.0556
p.S143F	DO51275	SKCM	ICGC	VLLYDE	LIG_APCC_ABBA_1	0.1944
p.W143L	DO229259	THCA	ICGC	VLLYDE	LIG_APCC_ABBA_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q16829	Dual specificity protein phosphatase 7	LIG_APCC_ABBA_1	133:138	VLLYDE	APC,CDC20,FZR1	0.7269	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons