DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
VLPTPTKT
Uniprot ID:
Q2M2H8
Source protein:
Probable maltase-glucoamylase 2
Source gene:
MGAM2
Class:
DEG_SCF_FBW7_1
Location:
1813:1820
E3 ligase:
FBXW7
DEGRON score:
0.7842
ASA_SCORE:
87.9875
COIL:
0.8718
CONS_SCORE:
0
DSS_SCORE:
0.55
HELIX:
0.0189
FCONS_SCORE:
0
RIG_SCORE:
0.7005
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MGAM2 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VLPTPTKT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q2M2H8
Probable maltase-glucoamylase 2
DEG_SCF_FBW7_1
1813:1820
VLPTPTKT
FBXW7
0.7842
More...